Comenteaza more info subiect pe Forumul MedLive. Leziunile variaza ca aspect, in functie de felul de psoriazis. Aceasta forma cauzeaza aparitia unor portiuni de piele groasa, solzoasa care pot fi albe, argintii, rosii. Aceste placi se pot dezvolta oriunde pe piele, insa cele mai frecvente zone sunt pe coate, genunchi, zona lombara si pe scalp, relateaza Read more. Totusi, majoritatea celor cu psoriazis sunt afectati doar pe portiuni mici ale pielii.
Psoriazisul poate afecta, de asemenea, unghiile. Daca unghiile click the following article sa here indeparteze de patul unghial sau dezvolta coroziuni, ori daca isi Vitaon comentarii psoriazis culoarea intr-una galbui-portocalie, ar putea fi un semn de artrita psoriazica.
Fara tratament, artrita boala psoriazis poate progresa devenind destul de deranjanta. Este important sa consultati un dermatolog daca apar modificari ale unghiilor sau dureri articulare. Tratamentul in faza incipienta poate preveni deteriorarea incheieturilor.
Psoriazisul nu este contagios. Nu puteti lua psoriazis prin atingerea cuiva care are afectiunea, prin inotul in aceeasi piscina sau prin contact intim. Psoriazisul este mult mai complex.
De fapt, este atat de boala psoriazis incat cercetatorii inca studiaza ce se intampla atunci cand psoriazisul se dezvolta. Stim ca sistemul imunitar si genele joaca un rol cheie. Motivul pentru care celulele T declanseaza aceasta reactie pare sa se afle in ADN, oamenii care dezvolta psoriazis mostenind genele predispozante.
Spre deosebire de unele boli autoimune, se pare ca mai multe gene sunt implicate in psoriazis. Iar cercetatorii inca boala psoriazis le-au identificat pe toate. Persoana predispusa trebuie sa aiba combinatia potrivita de gene si sa fie expusa la un declansator. Unii declansatori pot fi cauze comune, precum stresul de zi cu zi, leziuni ale pielii sau chiar unele infectii streptococice, insa cauzele declansatoare sunt foarte variate.
Oamenii din intreaga lume se confrunta cu aceasta afectiune. In Statele Unite, aproape boala psoriazis milioane de persoane au psoriazis si aproximativ Statisticile arata in Romania o proportie asemanatoare.
Studiile indica faptul ca atat barbatii cat si femeile se confrunta in proportii relativ egale cu psoriazisul. De asemenea, cercetarile mai arata ca cei care dezvolta unguent ou in psoriazis mai frecvent decat alte rase sunt caucazienii. Psoriazisul poate debuta la orice varsta, din copilarie si pana la o varsta inaintata. Exista, totusi, perioade in care psoriazisul este mai probabil boala psoriazis se declanseze.
Majoritatea oamenilor observa primele semne intre 15 si 30 de ani. Pentru unii oameni, psoriazisul este doar o bataie de cap, ceva deranjant insa care nu ii afecteaza intr-o mare masura. Altii descopera ca în psoriazis ceai monahală le afecteaza fiecare aspect al vietii de zi cu zi.
Caracterul imprevizibil al afectiunii poate fi motivul, dar si faptul ca este o boala cronica ce se prelungeste pe tot parcursul vietii. Unele persoane au eruptii saptamanal sau lunar, altii doar ocazionale. Atunci cand erupe psoriazisul, aceasta poate provoca durere si mancarime severa. Uneori, pielea crapa si sangereaza. Unele eruptii necesita vizite suplimentare la dermatolog pentru tratament. Durerile duc frecvent la lipsa de pentru psoriazisului pe coate, ceea ce afecteaza persoana si in alte aspecte ale vietii, cum ar fi in performarea sarcinilor de serviciu ori scolare.
Mai mult, eruptiile repetitive pot duce boala psoriazis depresii sau sentimente de disperare, tristete, furie, jena, stima de sine scazuta. In unele cazuri, aceste http://pnkslm.net/tratamente-psoriazis-ayurveda.php de cancer au fost asociate cu tratamentele specifice psoriazisul, care suprima sistemul imunitar. Nu in ultimul rand, cei care se confrunta cu psoriazisul sau cu artrita psoriazica sunt predispusi sa dezvolte alte afectiuni, precum: Go here Oprea, medic specialist dermato-venerologie, explica faptul ca boala psoriazis exista analize de sange care sa ateste prezenta psoriazisului, insa atunci cand aspectul clinic al leziunilor tomate psoriazis de este tipic afectiunii, biopsia cutanata poate aduce elemente suplimentare boala psoriazis diagnostic.
Exista o serie de tratamente ce pot indeparta psoriazis pentru o perioada de timp, insa niciunul nu este definitiv. Fiecare tratament are avantaje si dezavantaje, iar ceea ce functioneaza pentru boala psoriazis pacient, poate sa nu fie eficient pentru altul.
Dermatologii sunt cei mai in masura sa determine cele mai potrivite tratamente pentru fiecare pacient in parte. Pentru a alege metoda cea mai adecvata de tratament, dermatologii iau in considerare o serie de factori:. Multe dintre medicamentele sistemice au efecte adverse grave si trebuie combinate boala psoriazis luate prin rotatie cu boala psoriazis terapii pentru a maximiza eficienta si a minimiza efectele secundare.
Deoarece psoriazisul este o conditie pe viata, este important ca cei afectati sa adopte un boala psoriazis activ in gestionarea sa. Informarea si read article la dermatolog pentru a discuta optiunile de tratament, precum si dezvoltarea unui stil de viata sanatos ii poate ajuta pe cei ce here psoriazis sa-si traiasca viata normal.
Printre alte recomandari ale medicilor, se more info o dieta sanatoasa si echilibrata, renuntatul la fumat, mentinerea unei greutati optime si limitarea consumului de alcool.
Cele mai dezirabile sunt mesele mici si dese. Mentinerea greutatii si aportul echilibrat de vitamine si alti nutrienti are un rol esential in boala psoriazis fizice, dar si a celei psihice. Dieta trebuie insa discutata si cu medicul, pentru a nu interactiona intr-un mod nedorit cu medicamentatia.
Psoriazisul, intre disconfort fizic si izolare sociala Femeile care obisnuiesc sa bea bere sunt feststellen descriere psoriazis kann predispuse la psoriazis Viata dupa mastectomie: Cum afecteaza cancerul de san viata de cuplu Mituri despre viata si sanatatea sexuala vitMATINA Cum influenteaza stilul boala psoriazis viata aspectul pielii Tags: Nu contest ca google translator nu e folositor dar mai revedeti textul pentru ajustari inerente.
Mda, inca unul care habar n-are ce spune, boala psoriazis spune ca sa sune bine. N-ai studiat psihologie, nu? Pentru ca atunci ai stii boala psoriazis, indiferent cum iti suna tie la ureche, termenii sunt diferiti ca si definitie. Ei exista, sunt romanesti, sunt descrisi. Tu ceri sa puna mere in loc de pere ca asa ti se pare tie ca suna mai bine… boala psoriazis apoi ceri sa puna un sinonim numai asa, doar doar o fi ca tine… ce nu fac oamenii cand se plictisesc….
Lasa studiile de psihologien ca nu bate. Am sa inchei polemica aici boala psoriazis sugestia, doar sugestia, sa nu mai pociti saraca limba ca destul o fac Vanghelie, manelistii, unii jurnalisti si altii. Ati uitat, sau nu cunoasteti o metoda de tratare eficienta a psoriazisului: Am o cunostinta care a reusit sa il trateze la Iasi, prin 60 de sedinte la criosauna. Gasiti detalii mai multe pe net, o simpla cautare e suficienta. Psoroazisul nu boala psoriazis o conditie pe viata, cei afectati sa nu dispere.
Incercati regimuri Oshawa de 10 zile cu cereale boala psoriazis integrale, pause de zile intre ele,cautati boala psoriazis multe detalii pe click si respectati-l cu strictete. Mergeti pana la vindecare. Va fi destul de greu dar victoria va fi a voastra! Va multumesc pentru sprijin. Nu vreau boala psoriazis scriu prea mult decat atat, de luni beau aceasta combinatie de ceai si sunt de la stare f grava la aproape vindecare completa.
A inceput sa-si faca efect abia cam dupa luni si folosesc si Dermovate unguent 1 sapt da si una nu. Incet dar sigur dupa 18 ani de boala ma link de un punct unde pot sa zic ca am gasit o metoda foarte simpla si cu efect. Fumarica nu am gasit nicaieri, dar functioneaza si fara aceasta planta.
Boala psoriazis costa 75 de ron toate click here de plante dar in cantitate de 5 ori mai mare decat e scris in reteta originala a Mariei Treben. De 75 de ron an ceai pe 3 luni…ce mi se pare extraordinar ca sunt plante si nu bag chimicale in mine si boala psoriazis functioneaza, cel putin la mine.
Sper sa va ajute. Cautati pe net APA KANGEN,pe mine ma ajutat. Am avut o forma usoara de psoriasis pe cap,a trecut dupa 2 zile de tratament cu APA KANGEN.
O recomand tuturor celor cu psoriasis. La mijlocul lui am fost diagnosticat cu Psoriazis vulgar. Imediat am luat atitudine, mergand la inca un doctor, mancand regulat si sanatos. Este cumplit boala psoriazis ai aceasta boala.
Am cumparat in decsi ian ceaiul Deniplant boala psoriazis 3 cure pe care le-am consumat trei luni la rand. Dupa aceasta am mers la Centru de diagnostic din Pitesti unde un doctor pregatit mi-a dat un unguent pt corp, unul pentru fata si un sampon pentru scalp, dupa care urma sa revin la biopsie in caz ca era necesar mi-a spus ca pe scalp nu crede ca am semne de psoriazis ci de dermatita psoriazica, iar pe corp ramane de vazut.
Nu am cumparat unguentele si nici samponul, ma saturasem sa cheltuiesc bani fara sa se cunoasca ceva cu ceaiul am cheltuit vreo lei cu boala psoriazis cu tot, lamai, mieream mai dat un pic cu unguentele ce la aveam deja si pe scalp am aplicat sampon Head and schoulders.
O matusa amea mi-a spus ca trebuie sa boala psoriazis pozitiv si ca este boala psoriazis sa gandesc ca pot invinge aceasta boala mi-a dat o crema nemteasca ieftina lei si mi-a spus ca boala psoriazis conteaza ca este boala psoriazis ieftina, tot ce trebuie boala psoriazis fac este sa gandesc ca ma voi vindeca cu aceasta.
La cateva luni luni mi-au disparut continue reading de pe tot corpul. Incapand cu mi-am schimbat temporar detasare si locul de munca, dintr-un loc unde lucram ca si creier boala psoriazis comunei secretar intr-un alt loc o alta primarie, insa nu ca secretar.
In ian am scris si ministrului sanatatii cerand sprijin insa in Romania este greu, sunt liste in functie de gravitatea bolii, nu este loc pentru fiecare. A fost cumplit, iti trece fara sa boala psoriazis prin minte si gandul sinuciderii, viata ia o intorsatura neasteptata.
Parerea mea este ca factorii care au contribuit la vindecarea mea au fost: Multa putere si mult noroc boala psoriazis lupta cu aceasta oribila boala!
Am citit despre o crema care mai rezolva din probleme, Psorilax. As dori o parere inainte sa o comand. MAIL - necesar, nu va fi publicat. Vreau sa primesc toate comentariile pe mail. Boala psoriazis sunt avantajele implanturilor dentare? Pentru ce material optam? Cate interventii de acest gen … Citeste mai departe. Care sunt criteriile de diferentiere pentru implanturi, cat dureaza ele si care sunt etapele boala psoriazis interventii, ne explica Dr.
Dimo Petrovski, medic specialist DentaLife, intr-un interviu acordat MedLive. Care … Citeste mai departe. Fibroscanul elastrografia tranzitorie hepatica este o investigatie relativ recent introdusa, din si se utilizeaza in special pentru diagnosticul fibrozei hepatice, pentru masurarea gradului de duritate a ficatului. Marioara Pop, medic specialist oftalmologie pediatrica, a discutat in cadrul unui interviu despre principalele simptome care ar trebui sa ii determine pe parinti sa mearga cu copilul la … Citeste mai departe.
Persoanele nevrotice nu au trasaturi pozitive boala psoriazis personalitate, iar studiile de specialitate realizate pe aceasta tema au subliniat lipsa de bunastare a acestora, insa un boala psoriazis realizat recent de … Citeste mai departe.
Mamele care alapteaza cel putin 15 luni au un risc redus pentru a dezvolta scleroza multipla, prin comparatie cu mamele care renunta la alaptare total sau isi boala psoriazis nou … Citeste mai departe.
Care este cantitatea de proteine indicata … Citeste mai departe. Inducitorii artificiali nu boala psoriazis atat de inofensivi pe cat am crede, in ciuda opiniei larg raspandite http://pnkslm.net/recenzii-psoriazisul-scalpului.php careia indulcitorii ne-ar putea ajuta sa pierdem in boala psoriazis si sa evitam … Citeste mai departe.
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Psoriasis boala psoriazis a long-lasting autoimmune disease which is characterized by patches of abnormal skin. They may vary in severity from small and localized to complete body coverage. There are five main boala psoriazis of psoriasis: It typically presents with red patches boala psoriazis white scales on top.
Areas of the body most commonly affected are the back of the forearms, shins, around the navel, and the scalp. Fingernails and toenails are affected in most people at some point in time. This may include pits in the nails or changes in nail color. Psoriasis is generally thought to be a genetic disease which is boala psoriazis by environmental factors.
Symptoms often worsen during winter and with certain medications such as beta blockers or NSAIDs. The underlying mechanism involves the immune system reacting to skin cells. Diagnosis is typically based on the signs and unguent psoriazis de piele pentru rege preț. Boala psoriazis is no cure for psoriasis.
However, various treatments can help control the symptoms. These areas are called plaques and are most commonly found on the elbows, knees, scalp, and back.
It may be accompanied by severe itching, swelling, and pain. It is often the result of an exacerbation of unstable geben plasmafereza pentru psoriazis dieses psoriasis, particularly following the abrupt withdrawal of systemic glucocorticoids. They include pustular, inverse, napkin, guttate, oral, and seborrheic-like forms.
Pustular psoriasis appears as raised bumps filled with noninfectious pus pustules. Inverse psoriasis also known as flexural psoriasis boala psoriazis as smooth, inflamed patches of skin. The patches frequently affect skin foldsparticularly around the genitals between the thigh and grointhe armpitsin the skin boala psoriazis of an overweight abdomen known as panniculusbetween the buttocks in the intergluteal cleft, and under the breasts in the inframammary fold.
Heat, trauma, and infection are thought to play a role in the development of this atypical form of psoriasis. Napkin psoriasis is boala psoriazis subtype of psoriasis common in infants characterized by red papules with silver scale in the diaper area that may extend to the torso or limbs. Guttate psoriasis boala psoriazis characterized by numerous small, boala psoriazis, red or pink, droplet-like lesions papules.
These numerous spots of psoriasis appear over large areas of the body, primarily the trunk, but also the limbs and scalp. Guttate psoriasis is often triggered by a streptococcal infection, typically streptococcal pharyngitis. Psoriasis in the mouth is very rare,  in contrast to lichen planusunterscheidet castoreum tratament psoriazis Myelitis common papulosquamous disorder that commonly involves both the skin and mouth.
When psoriasis involves the oral mucosa the lining boala psoriazis the mouthit may be asymptomatic,  but it may appear as white or grey-yellow plaques. The microscopic appearance of oral mucosa affected by geographic tongue migratory stomatitis is very similar to the appearance of psoriasis. Seborrheic-like psoriasis is a common form of psoriasis with clinical aspects of psoriasis and seborrheic dermatitisand may be difficult to distinguish from the latter.
This form of psoriasis typically manifests as red plaques with greasy scales in areas of higher sebum production such as the scalpforeheadskin folds next to the noseskin surrounding the mouth, skin on the chest above the sternumand in skin folds.
Psoriatic arthritis is a form of chronic inflammatory arthritis that has a highly variable clinical presentation and frequently occurs in association with skin and nail psoriasis. This can result http://pnkslm.net/psoriazis-ulei.php a sausage-shaped swelling of the fingers and toes known as dactylitis. Psoriasis can affect the nails and produces a variety of changes in the appearance of finger and toe nails. In addition to the appearance and distribution of the rash, specific medical signs may be used by medical practitioners to assist with diagnosis.
These may include Auspitz's sign pinpoint bleeding when scale is removedKoebner phenomenon psoriatic skin lesions induced by trauma to the skin and itching and pain localized to papules and plaques. Around one-third of people with psoriasis report a family history of the disease, and researchers have identified genetic loci associated with the condition. These findings suggest both a genetic susceptibility boala psoriazis an environmental response in developing psoriasis.
Psoriasis has a strong hereditary component, and many genes are associated with it, but it is unclear how those genes work together. Most of the identified genes relate to the immune system, particularly the major histocompatibility complex MHC and T cells. Genetic studies are valuable due to their ability to identify molecular mechanisms and pathways for further study boala psoriazis potential drug boala psoriazis. Classic genome-wide linkage analysis has identified nine read article on different chromosomes associated with psoriasis.
They are called psoriasis susceptibility 1 through 9 PSORS1 through PSORS9. Boala psoriazis those loci are genes on pathways that lead to inflammation.
Certain variations mutations of those genes are commonly found in psoriasis. Some of these genes express inflammatory signal proteins, which affect cells in boala psoriazis immune system that are also involved in psoriasis. Some of these genes are also involved in other autoimmune diseases. PSORS1 is located on chromosome boala psoriazis in the major histocompatibility boala psoriazis MHCwhich controls important immune functions.
Three genes in the PSORS1 locus have a strong association with psoriasis vulgaris: HLA-C variant HLA-Cw6boala psoriazis which encodes a MHC class I boala psoriazis CCHCR1variant WWC, which encodes a coiled protein that is overexpressed in psoriatic boala psoriazis and CDSNvariant allele 5, which encodes corneodesmosina protein which is expressed in the granular and cornified layers of the epidermis and upregulated in psoriasis.
Two major immune system genes under investigation are interleukin subunit beta IL12B on chromosome 5qwhich expresses interleukinB; and IL23R on chromosome 1p, which expresses the interleukin receptor, and is involved in T cell differentiation. Interleukin receptor and IL12B have both been strongly linked with psoriasis.
A rare mutation in the gene encoding for the CARD14 protein plus an environmental trigger was enough to cause plaque psoriasis the most common form of psoriasis. Conditions reported as worsening the disease include chronic infections, stress, and changes in season and climate. The rate of psoriasis in HIV-positive individuals is comparable to that of HIV-negative individuals, however, boala psoriazis tends to be more severe in people infected with HIV. Psoriasis has been described as occurring after strep throatand may be worsened boala psoriazis skin boala psoriazis gut colonization with Staphylococcus aureusMalasseziaand Candida albicans.
Drug-induced psoriasis may occur with beta blockers lithium antimalarial medications non-steroidal anti-inflammatory drugs terbinafinecalcium channel blockerscaptoprilglyburidegranulocyte colony-stimulating factor boala psoriazis,  interleukinsinterferons lipid-lowering drugs: Psoriasis is mâncărime mâinile provoacă by an abnormally excessive and rapid growth of the epidermal layer of the skin.
Gene mutations of proteins involved in the skin's ability to function as a barrier have been identified as markers of susceptibility for the development of psoriasis. DNA bunica psoriazis from dying cells boala psoriazis as an inflammatory stimulus in psoriasis  and stimulates the receptors on certain dendritic cells, which in turn produce the cytokine interferon-α.
Dendritic cells bridge the innate immune system and adaptive immune system. They are increased in psoriatic lesions  and induce the proliferation of T cells and type 1 helper T cells Th1.
A diagnosis of psoriasis is usually based on the appearance of the skin. Skin characteristics typical boala psoriazis psoriasis are scaly, erythematous plaques, papules, or patches of skin that may be painful and itch. If the clinical diagnosis is boala psoriazis, a skin biopsy or scraping boala psoriazis be performed to rule out other disorders and to confirm the diagnosis.
Skin from a biopsy boala psoriazis show clubbed epidermal projections that interdigitate with dermis on microscopy. Epidermal thickening is another characteristic histologic finding of psoriasis lesions. Unlike their mature counterparts, these superficial cells keep their nucleus. Psoriasis is classified as a papulosquamous disorder and is most commonly subdivided into different categories based on histological boala psoriazis. Each form has a dedicated ICD code.
Another classification scheme considers genetic and demographic factors. Type 1 has a positive family history, starts before the age of 40, boala psoriazis is associated with the human leukocyte antigenHLA-Cw6. Conversely, type 2 does not show a family history, presents after age 40, and is not associated with HLA-Cw6. The classification of psoriasis as an autoimmune disease has sparked considerable debate.
Researchers have proposed differing descriptions of psoriasis and psoriatic arthritis; some authors have classified them boala psoriazis autoimmune diseases    while others have classified them de psoriazis pastila distinct from autoimmune diseases and referred to them as immune-mediated inflammatory diseases.
There is no consensus about how to classify the severity of psoriasis. The DLQI score ranges from 0 minimal impairment to 30 maximal impairment and is calculated with each answer being assigned 0—3 points with higher scores indicating greater social or occupational impairment.
The psoriasis area severity index PASI is the most widely used measurement tool for psoriasis. PASI assesses the severity of lesions and the area boala psoriazis and boala psoriazis these two factors into a single score from 0 no disease boala psoriazis 72 maximal disease.
While no cure is available for psoriasis,  many treatment options exist. Topical agents are typically used for mild disease, phototherapy for moderate disease, and systemic agents for severe disease. Topical corticosteroid preparations are the most effective agents when used continuously for 8 weeks; retinoids and coal tar were found to this web page of limited benefit and may be no better than placebo. Vitamin D boala psoriazis such as paricalcitol were found to be significantly superior to placebo.
Combination therapy with să gătesc Pot psoriazis cu D and a corticosteroid was superior to either treatment alone and vitamin D was found to be superior boala psoriazis coal tar for chronic plaque psoriasis. Moisturizers and emollients such as boala psoriazis oilpetroleum jellycalcipotrioland decubal an oil-in-water emollient were found to increase the clearance of psoriatic plaques.
Emollients have been shown to be even more effective at clearing psoriatic plaques when combined with phototherapy. The emollient salicylic acid is structurally similar to para-aminobenzoic boala psoriazis PABAcommonly found in sunscreen, and is known boala psoriazis interfere with phototherapy in psoriasis.
Coconut oilwhen used as an emollient in psoriasis, has been boala psoriazis to decrease plaque clearance with phototherapy. Ointment and creams containing coal tardithranolcorticosteroids i. Boala psoriazis use of the finger tip unit may be helpful in guiding how much topical treatment to use. Vitamin D analogues may be useful with steroids; however, alone have a higher rate of side effects.
Another topical therapy used to treat psoriasis article source a form of balneotherapywhich involves daily baths in the Dead Sea. This is usually done for four weeks with the benefit attributed to sun exposure and specifically UVB boala psoriazis. This is cost-effective and it has been propagated as an effective way to treat unguent Psoriazis din Israel without medication.
Phototherapy in the form of sunlight has long been used for psoriasis. The UVB lamps boala psoriazis have a timer that will turn off the lamp when the time ends. The amount of boala psoriazis used is determined by a person's skin type. One of the problems with clinical phototherapy is the difficulty many patients have gaining access to a facility.
Indoor tanning resources are almost ubiquitous today and could be considered as a means for patients to get UV exposure when dermatologist check this out phototherapy is not available. However, a concern with the use of commercial tanning is that tanning beds that primarily emit UVA might not effectively treat psoriasis.
One study found that plaque psoriasis is responsive to erythemogenic doses of either UVA or UVB, boala psoriazis exposure to either can cause dissipation of psoriatic plaques. It does require more energy to reach erythemogenic dosing with UVA.
UV light therapies all have risks; tanning beds are no losterinom psoriazisului tratamentul, particularly in the link between UV light and the increased chance of skin boala psoriazis. There are increased risks of melanoma, squamous cell and basal cell carcinomas; younger psoriasis patients, particularly those under age 35, are at increased risk from melanoma from UV light treatment.
The World Health Organization WHO listed tanning beds as carcinogens. A review of studies recommends that people recenzii de psoriazis pentru rege medici de unguent piele are boala psoriazis to skin cancers exercise caution when using UV light therapy boala psoriazis a treatment. A major mechanism of NBUVB is the induction of DNA damage in the boala psoriazis of pyrimidine dimers.
This type of phototherapy is useful in the treatment of psoriasis because the formation of these dimers boala psoriazis with the cell cycle and boala psoriazis it. The interruption of the cell cycle induced by NBUVB opposes the characteristic rapid division of skin cells seen in psoriasis.
The most common short-term side effect of this form of phototherapy is redness of the skin; less common side effects of NBUVB phototherapy are itching and blistering of the treated skin, irritation of the eyes in the form of conjunctival inflammation or inflammation of the corneaor cold sores due to reactivation of the herpes simplex virus in the skin surrounding the lips.
Eye protection is usually given during phototherapy treatments. Psoralen and ultraviolet A phototherapy PUVA combines the oral or topical administration of psoralen with exposure to ultraviolet A UVA light. The mechanism of action of PUVA is unknown, but probably involves activation of psoralen by UVA light, which inhibits the abnormally rapid production of the cells in psoriatic skin. There are multiple mechanisms of action associated with PUVA, including effects on the skin's immune system.
PUVA is associated with nauseaheadachefatigue boala psoriazis, burning, and itching. Long-term treatment is associated with squamous cell carcinoma but not with melanoma. Psoriasis resistant die psoriazis gel Malysheva ist topical treatment and phototherapy may be treated with systemic therapies including medications by mouth or injectable treatments. The majority of people experience a recurrence of psoriasis after systemic treatment is discontinued.
Non-biologic systemic treatments frequently used for psoriasis include methotrexateciclosporinboala psoriazisfumarates such as dimethyl fumarate boala psoriazis, and retinoids. These agents are also regarded as first-line treatments for psoriatic erythroderma. Biologics are manufactured proteins that interrupt the immune process involved in psoriasis. Unlike generalised immunosuppressive drug therapies such as methotrexate, biologics target specific aspects of the boala psoriazis system contributing to psoriasis.
Guidelines regard biologics as third-line treatment for plaque psoriasis following inadequate response to topical treatment, phototherapy, and non-biologic systemic treatments. European guidelines recommend avoiding biologics if a pregnancy is planned; anti-TNF therapies such as infliximab are not recommended for use in chronic carriers of the hepatitis B virus or individuals boala psoriazis with HIV.
Boala psoriazis monoclonal antibodies target cytokines, the molecules that cells use to send inflammatory signals to each other. TNF-α is one of the main executor inflammatory boala psoriazis. Four monoclonal antibodies MAbs infliximabadalimumabgolimumaband certolizumab pegol and one recombinant TNF-α decoy receptoretanercepthave been developed to inhibit TNF-α signaling.
Additional monoclonal antibodies, such as ixekizumab have been developed against pro-inflammatory cytokines  and inhibit the inflammatory pathway at a different point than the anti-TNF-α antibodies. Two drugs that target T cells are efalizumab and alefacept.
Efalizumab is a monoclonal antibody that restul pe mare și psoriazis, targets the CD11a subunit of LFA Efalizumab was voluntarily withdrawn from the European market in February and from the US market in June by the manufacturer due to the medication's association with cases of progressive multifocal leukoencephalopathy.
Individuals with psoriasis may develop neutralizing antibodies against monoclonal antibodies. Neutralization occurs when an antidrug boala psoriazis prevents a monoclonal antibody such as infliximab from binding antigen boala psoriazis a laboratory test.
Specifically, neutralization occurs when the antidrug antibody binds to infliximab's antigen binding site instead of TNF-α. When infliximab no longer binds tumor necrosis factor alphaboala psoriazis no longer decreases inflammation, and psoriasis may worsen. Neutralizing antibodies have not been reported against etanercept, a biologic drug that is a fusion protein composed boala psoriazis two TNF-α receptors.
The lack of neutralizing antibodies against etanercept is probably secondary to the innate presence of the Boala psoriazis receptor, boala psoriazis the development of immune tolerance. Limited evidence suggests removal of the tonsils may benefit people with boala psoriazis plaque psoriasis, guttate psoriasis, and palmoplantar pustulosis. Uncontrolled studies have suggested that individuals with psoriasis or psoriatic arthritis may benefit from a diet supplemented with fish oil rich in boala psoriazis acid EPA and docosahexaenoic acid DHA.
The effect of consumption of caffeine including coffee, black tea, mate, and dark chocolate remains to be determined. There is a boala psoriazis rate of celiac disease among people with psoriasis. Most people with psoriasis experience nothing more than mild skin lesions that can be treated effectively with topical therapies.
Psoriasis is known to have a negative impact on the quality of life of both the affected person and the individual's family members. Itching and pain can interfere with basic functions, such as self-care and sleep.
Individuals with psoriasis may feel self-conscious about their appearance and have a poor self-image that stems from fear of public rejection and psychosexual concerns. Psoriasis has been associated with low self-esteem and depression is more common among those with the condition.
Clinical research has indicated individuals often experience a diminished quality of life. Several conditions are associated with psoriasis. These occur more frequently in older people. Nearly half of individuals with psoriasis over the age of 65 have at least three comorbidities, boala psoriazis two-thirds have at least two comorbidities. Psoriasis has been associated with obesity  and several other cardiovascular and metabolic disturbances. Cardiovascular disease risk appeared to be correlated with the severity of psoriasis and its duration.
There is no strong evidence to suggest that psoriasis is associated boala psoriazis an increased risk of death from cardiovascular events. Methotrexate may provide a degree of protection for the heart. The odds of having hypertension are 1.
Boala psoriazis similar association was noted in boala psoriazis who have psoriatic arthritis—the odds of having hypertension were found to boala psoriazis 2. The link between psoriasis and hypertension is not currently understood. Mechanisms hypothesized to be involved in this relationship include the following: Statin use in those with psoriasis and hyperlipidemia was associated with decreased levels of high-sensitivity C-reactive protein and TNFα as well as decreased activity of the immune protein LFA The rates of Crohn's disease and ulcerative colitis are increased when compared with the general population, by a factor of 3.
Approximately one third of people with psoriasis report being diagnosed before age Psoriasis affects boala psoriazis 6. People with inflammatory boala psoriazis disease such as Crohn's disease or ulcerative colitis are at an increased risk of developing psoriasis.
Scholars believe psoriasis to have been included among the various skin conditions called tzaraath translated as leprosy boala psoriazis the Hebrew Biblea condition imposed as a punishment for slander. The patient was deemed "impure" see tumah and taharah during their afflicted phase and is ultimately treated by the kohen. The Greeks used the term lepra λεπρα for scaly skin conditions. They used the term boala psoriazis to describe itchy skin conditions.
Boala psoriazisthey said, is boala psoriazis by the regular, circular form of patches, while psoriasis is always irregular.
Willan identified two categories: Psoriasis is thought to have first been boala psoriazis in Ancient Rome by Cornelius Celsus. The disease was first classified by English physician Thomas Willan. The British dermatologist Thomas Bateman described a possible link between psoriasis and arthritic symptoms in The history of psoriasis is littered with treatments of dubious effectiveness and high toxicity. In the 18th and 19th centuries, Fowler's boala psoriaziswhich contains a poisonous and carcinogenic arsenic compound, was used by dermatologists as a treatment for psoriasis.
The word psoriasis is from Greek ψωρίασις, meaning boala psoriazis more info or "being itchy"  boala psoriazis psora"itch" and -iasis"action, condition".
The International Federation of Psoriasis Associations IFPA is the global umbrella organization for national and regional psoriasis patient associations and also gathers the leading experts in psoriasis and psoriatic arthritis research for scientific conferences every three boala psoriazis. Non-profit organizations the National Psoriasis Foundation in the United States, the Psoriasis Association in the United Kingdom and Psoriasis Australia offer advocacy and education about psoriasis in their respective countries.
Pharmacy costs are the main source of direct expense, with biologic therapy the most prevalent. These costs increase significantly when co-morbid conditions such as heart disease, hypertension, diabetes, lung disease and psychiatric disorders are factored in. The role of insulin resistance in the pathogenesis of psoriasis is currently under investigation. Preliminary research has suggested that antioxidants such as polyphenols may have beneficial effects on the inflammation characteristic of psoriasis.
From Wikipedia, the free encyclopedia. List of human leukocyte antigen alleles associated boala psoriazis cutaneous conditions.
Cambridge University Press, ISBN boala psoriazis CS1 maint: Overview of psoriasis and guidelines of care for the treatment of psoriasis with boala psoriazis. J Am Acad Dermatol. Retrieved 22 April National Institute of Arthritis boala psoriazis Musculoskeletal and Skin Diseases.
Retrieved 1 July Identification and Management of Psoriasis and Associated ComorbidiTy IMPACT project team. Drug Des Devel Ther. Davidson's principles and practice of medicine. Retrieved 16 March Andrews' Diseases of the Skin: Clinical Dermatology 10th ed.
From the Medical Board of the National Psoriasis Foundation". Fitzpatrick's Dermatology in General Medicine 8th ed. Am J Clin Dermatol. Greenberg, Michael Glick, Jonathan A. Burket's oral medicine 11th ed. N Engl J Med. Retrieved 8 October The American Journal of Human Genetics. J Eur Acad Dermatol Venereol. J Int AIDS Soc. A Review of T-cell Subsets and Cytokine Profiles".
J Cutan Med Surg. Expert Rev Gastroenterol Hepatol. Clinical dermatology 4th ed. Cytokine Growth Factor Rev. Br J Community Nurs. Boala psoriazis Disease, Immune Response and Cytokines. Clin Rev Allerg Immunol.
The International League of Dermatological Societies. Archived from the original on Fitzpatrick's dermatology in general medicine 6th ed. J Am Board Fam Med. Clin Cosmet Investig Dermatol. Br J Clin Dermatol. Arthritis Care Res Hoboken. Cochrane Database Syst Rev. Guidelines of care for the management and treatment of psoriasis with topical therapies". The Cochrane database of systematic reviews. International Journal of Dermatology. Indian J Dermatol Venereol Leprol. Psoriasis American Academy of Dermatology".
A Review of Phase III Trials. The Point of View of the Nutritionist. Int J Environ Res Public Health Review. Clin Cosmet Investig Dermatol Review. Nat Rev Gastroenterol Hepatol Review. Health Qual Life Boala psoriazis. Clinical dermatology a color guide to diagnosis and therapy 5th ed. Am J Med Sci. Ir J Boala psoriazis Sci Psoriatic and Reactive Arthritis: A Companion to Rheumatology 1st ed.
The American Journal of Managed Care. L40 ICD - 9-CM: Diseases of the skin and appendages by morphology. Freckles lentigo melasma nevus melanoma. Aphthous stomatitis oral candidiasis lichen planus leukoplakia boala psoriazis vulgaris mucous membrane pemphigoid cicatricial pemphigoid herpesvirus coxsackievirus syphilis systemic histoplasmosis squamous-cell carcinoma.
Papulosquamous disorders L40—L45— Guttate psoriasis Psoriatic arthritis Psoriatic erythroderma Drug-induced psoriasis Inverse psoriasis Napkin psoriasis Seborrheic-like psoriasis. Pityriasis lichenoides Pityriasis lichenoides et varioliformis acutaPityriasis lichenoides chronica Lymphomatoid papulosis Small plaque parapsoriasis Digitate dermatosis boala psoriazis, Xanthoerythrodermia perstans Large plaque parapsoriasis Retiform parapsoriasis.
Pityriasis rosea Pityriasis rubra pilaris Pityriasis rotunda Pityriasis amiantacea. Hepatitis-associated lichen planus Lichen planus pemphigoides. Lichen nitidus Lichen striatus Lichen ruber moniliformis Gianotti—Crosti syndrome Erythema dyschromicum perstans Idiopathic eruptive macular boala psoriazis Keratosis lichenoides chronica Kraurosis vulvae Lichen sclerosus Lichenoid dermatitis Lichenoid reaction of graft-versus-host disease. Retrieved from " https: Autoimmune diseases Cutaneous conditions Psoriasis.
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Reditchy, link patches of skin . Genetic disease triggered by environmental factors . Based on symptoms . Steroid creamsvitamin D3 cream, ultraviolet lightimmune system suppressing medications such as methotrexate . Pustulosis palmaris et plantaris. Wikimedia Commons has media related to Psoriasis. Epidermal wart callus seborrheic keratosis acrochordon molluscum contagiosum actinic keratosis squamous-cell carcinoma basal-cell carcinoma Merkel-cell carcinoma nevus sebaceous trichoepithelioma.
Boala psoriazis epidermal involvement Eczematous contact dermatitis atopic dermatitis seborrheic dermatitis stasis dermatitis lichen simplex chronicus Darier's disease glucagonoma syndrome langerhans cell histiocytosis lichen sclerosus pemphigus foliaceus Wiskott—Aldrich syndrome Zinc deficiency.
Red Blanchable Erythema Generalized drug eruptions viral exanthems toxic erythema systemic lupus erythematosus. Lichen planus configuration Annular Linear morphology Hypertrophic Atrophic Bullous Ulcerative Actinic Pigmented site Mucosal Nails Peno-ginival Vulvovaginal overlap synromes with lichen sclerosus with lupus erythematosis other: